Update on pharmacotherapy for ocular surface squamous neoplasia

The most frequently encountered non-pigmented tumor of the ocular surface is ocular surface squamous neoplasia (OSSN). Over the past two decades, the pharmacological management of OSSN has grown, with topical 5-fluorouracil, mitomycin, and interferon alpha 2b all being successfully used to treat thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Al Bayyat, Ghada, Arreaza-Kaufman, Dan, Venkateswaran, Nandini, Galor, Anat, Karp, Carol L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689886/
https://www.ncbi.nlm.nih.gov/pubmed/31417938
http://dx.doi.org/10.1186/s40662-019-0150-5
_version_ 1783443108361404416
author Al Bayyat, Ghada
Arreaza-Kaufman, Dan
Venkateswaran, Nandini
Galor, Anat
Karp, Carol L.
author_facet Al Bayyat, Ghada
Arreaza-Kaufman, Dan
Venkateswaran, Nandini
Galor, Anat
Karp, Carol L.
author_sort Al Bayyat, Ghada
collection PubMed
description The most frequently encountered non-pigmented tumor of the ocular surface is ocular surface squamous neoplasia (OSSN). Over the past two decades, the pharmacological management of OSSN has grown, with topical 5-fluorouracil, mitomycin, and interferon alpha 2b all being successfully used to treat this disease. Other agents, such as anti-vascular endothelial growth factor (VEGF), retinoic acid, cidofovir and Aloe vera, have less frequently been used in the treatment of OSSN. This review will discuss these pharmacologic agents, summarizing available data and presenting the approach to the treatment of these tumors.
format Online
Article
Text
id pubmed-6689886
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-66898862019-08-15 Update on pharmacotherapy for ocular surface squamous neoplasia Al Bayyat, Ghada Arreaza-Kaufman, Dan Venkateswaran, Nandini Galor, Anat Karp, Carol L. Eye Vis (Lond) Review The most frequently encountered non-pigmented tumor of the ocular surface is ocular surface squamous neoplasia (OSSN). Over the past two decades, the pharmacological management of OSSN has grown, with topical 5-fluorouracil, mitomycin, and interferon alpha 2b all being successfully used to treat this disease. Other agents, such as anti-vascular endothelial growth factor (VEGF), retinoic acid, cidofovir and Aloe vera, have less frequently been used in the treatment of OSSN. This review will discuss these pharmacologic agents, summarizing available data and presenting the approach to the treatment of these tumors. BioMed Central 2019-08-12 /pmc/articles/PMC6689886/ /pubmed/31417938 http://dx.doi.org/10.1186/s40662-019-0150-5 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Al Bayyat, Ghada
Arreaza-Kaufman, Dan
Venkateswaran, Nandini
Galor, Anat
Karp, Carol L.
Update on pharmacotherapy for ocular surface squamous neoplasia
title Update on pharmacotherapy for ocular surface squamous neoplasia
title_full Update on pharmacotherapy for ocular surface squamous neoplasia
title_fullStr Update on pharmacotherapy for ocular surface squamous neoplasia
title_full_unstemmed Update on pharmacotherapy for ocular surface squamous neoplasia
title_short Update on pharmacotherapy for ocular surface squamous neoplasia
title_sort update on pharmacotherapy for ocular surface squamous neoplasia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689886/
https://www.ncbi.nlm.nih.gov/pubmed/31417938
http://dx.doi.org/10.1186/s40662-019-0150-5
work_keys_str_mv AT albayyatghada updateonpharmacotherapyforocularsurfacesquamousneoplasia
AT arreazakaufmandan updateonpharmacotherapyforocularsurfacesquamousneoplasia
AT venkateswarannandini updateonpharmacotherapyforocularsurfacesquamousneoplasia
AT galoranat updateonpharmacotherapyforocularsurfacesquamousneoplasia
AT karpcaroll updateonpharmacotherapyforocularsurfacesquamousneoplasia

Ejemplares similares