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Brain Imaging and Impulse Control Disorders in Parkinson’s Disease

PURPOSE OF REVIEW: Parkinson’s disease (PD) has a wide spectrum of symptoms including the presence of psychiatric disease. At present, most treatment plans, comprised of dopaminergic drugs, are chronic and complex. Though dopaminergic agents are quite efficient in managing the motor aspects of the d...

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Autores principales: Roussakis, Andreas–Antonios, Lao–Kaim, Nicholas P., Piccini, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689903/
https://www.ncbi.nlm.nih.gov/pubmed/31396719
http://dx.doi.org/10.1007/s11910-019-0980-5
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author Roussakis, Andreas–Antonios
Lao–Kaim, Nicholas P.
Piccini, Paola
author_facet Roussakis, Andreas–Antonios
Lao–Kaim, Nicholas P.
Piccini, Paola
author_sort Roussakis, Andreas–Antonios
collection PubMed
description PURPOSE OF REVIEW: Parkinson’s disease (PD) has a wide spectrum of symptoms including the presence of psychiatric disease. At present, most treatment plans, comprised of dopaminergic drugs, are chronic and complex. Though dopaminergic agents are quite efficient in managing the motor aspects of the disease, chronic pharmacotherapy specifically with dopamine receptor agonists has been highly linked to the occurrence of Impulse Compulsive disorder (ICD), which can be problematic for individual patients. RECENT FINDINGS: Much of what is known today about PD-related ICD stems from brain imaging studies, however, evidence is not quite conclusive. Research in the field has been focused on identifying the underlying mechanisms of PD-related ICD and understanding the functions of the structures involved in the reward network. SUMMARY: This article presents an update of recent findings from key neuroimaging studies in PD-related ICD, discusses results from controversial studies, and identifies areas for future research in the field.
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spelling pubmed-66899032019-08-23 Brain Imaging and Impulse Control Disorders in Parkinson’s Disease Roussakis, Andreas–Antonios Lao–Kaim, Nicholas P. Piccini, Paola Curr Neurol Neurosci Rep Neuroimaging (N. Pavese, Section Editor) PURPOSE OF REVIEW: Parkinson’s disease (PD) has a wide spectrum of symptoms including the presence of psychiatric disease. At present, most treatment plans, comprised of dopaminergic drugs, are chronic and complex. Though dopaminergic agents are quite efficient in managing the motor aspects of the disease, chronic pharmacotherapy specifically with dopamine receptor agonists has been highly linked to the occurrence of Impulse Compulsive disorder (ICD), which can be problematic for individual patients. RECENT FINDINGS: Much of what is known today about PD-related ICD stems from brain imaging studies, however, evidence is not quite conclusive. Research in the field has been focused on identifying the underlying mechanisms of PD-related ICD and understanding the functions of the structures involved in the reward network. SUMMARY: This article presents an update of recent findings from key neuroimaging studies in PD-related ICD, discusses results from controversial studies, and identifies areas for future research in the field. Springer US 2019-08-08 2019 /pmc/articles/PMC6689903/ /pubmed/31396719 http://dx.doi.org/10.1007/s11910-019-0980-5 Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Neuroimaging (N. Pavese, Section Editor)
Roussakis, Andreas–Antonios
Lao–Kaim, Nicholas P.
Piccini, Paola
Brain Imaging and Impulse Control Disorders in Parkinson’s Disease
title Brain Imaging and Impulse Control Disorders in Parkinson’s Disease
title_full Brain Imaging and Impulse Control Disorders in Parkinson’s Disease
title_fullStr Brain Imaging and Impulse Control Disorders in Parkinson’s Disease
title_full_unstemmed Brain Imaging and Impulse Control Disorders in Parkinson’s Disease
title_short Brain Imaging and Impulse Control Disorders in Parkinson’s Disease
title_sort brain imaging and impulse control disorders in parkinson’s disease
topic Neuroimaging (N. Pavese, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689903/
https://www.ncbi.nlm.nih.gov/pubmed/31396719
http://dx.doi.org/10.1007/s11910-019-0980-5
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