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Immunologic Alterations Associated With Oral Delivery of Anti-CD3 (OKT3) Monoclonal Antibodies in Patients With Moderate-to-Severe Ulcerative Colitis

AIM: The aim of this study was to determine the immunologic effects and safety of oral anti-CD3 in patients with ulcerative colitis (UC). METHODS: An open-label pilot study of orally delivered anti-CD3 was performed in patients with moderate-to-severe UC. The primary end points were changes in immun...

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Detalles Bibliográficos
Autores principales:	Boden, Elisa K, Canavan, James B, Moran, Christopher J, McCann, Katelyn, Dunn, William A, Farraye, Francis A, Ananthakrishnan, Ashwin N, Yajnik, Vijay, Gandhi, Roopali, Nguyen, Deanna D, Bhan, Atul K, Weiner, Howard L, Korzenik, Joshua R, Snapper, Scott B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Observations and Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690423/ https://www.ncbi.nlm.nih.gov/pubmed/31423487 http://dx.doi.org/10.1093/crocol/otz009

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