Inaccuracy of the log‐rank approximation in cancer data analysis

The log‐rank test statistic is very broadly used in biology. Unfortunately, P‐values based on the popular chi‐square approximation are often inaccurate and can be misleading. [Image: see text]

Detalles Bibliográficos
Autores principales: Rappoport, Nimrod, Shamir, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690426/
https://www.ncbi.nlm.nih.gov/pubmed/31464374
http://dx.doi.org/10.15252/msb.20188754
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author Rappoport, Nimrod
Shamir, Ron
author_facet Rappoport, Nimrod
Shamir, Ron
author_sort Rappoport, Nimrod
collection PubMed
description The log‐rank test statistic is very broadly used in biology. Unfortunately, P‐values based on the popular chi‐square approximation are often inaccurate and can be misleading. [Image: see text]
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spelling pubmed-66904262019-08-15 Inaccuracy of the log‐rank approximation in cancer data analysis Rappoport, Nimrod Shamir, Ron Mol Syst Biol Correspondence The log‐rank test statistic is very broadly used in biology. Unfortunately, P‐values based on the popular chi‐square approximation are often inaccurate and can be misleading. [Image: see text] John Wiley and Sons Inc. 2019-08-12 /pmc/articles/PMC6690426/ /pubmed/31464374 http://dx.doi.org/10.15252/msb.20188754 Text en © 2019 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Correspondence
Rappoport, Nimrod
Shamir, Ron
Inaccuracy of the log‐rank approximation in cancer data analysis
title Inaccuracy of the log‐rank approximation in cancer data analysis
title_full Inaccuracy of the log‐rank approximation in cancer data analysis
title_fullStr Inaccuracy of the log‐rank approximation in cancer data analysis
title_full_unstemmed Inaccuracy of the log‐rank approximation in cancer data analysis
title_short Inaccuracy of the log‐rank approximation in cancer data analysis
title_sort inaccuracy of the log‐rank approximation in cancer data analysis
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690426/
https://www.ncbi.nlm.nih.gov/pubmed/31464374
http://dx.doi.org/10.15252/msb.20188754
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