Cargando…

Crystal structure analysis of the biologically active drug molecule riluzole and riluzolium chloride

This study is an investigation into the crystal structure of the biologically active drug molecule riluzole [RZ, 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine], C(8)H(5)F(3)N(2)OS, and its derivative, the riluzolium chloride salt [RZHCl, 2-amino-6-(trifluoromethoxy)-1,3-benzothiazol-3-ium...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mondal, Pradip Kumar, T, Athulbabu, Rao, Varun, Chopra, Deepak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2019
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690469/ https://www.ncbi.nlm.nih.gov/pubmed/31417770 http://dx.doi.org/10.1107/S2056989019009022

Ejemplares similares

Decachlorocyclopentasilanes coordinated by pairs of chloride anions, with different cations, but the same solvent molecules
por: Moxter, Maximilian, et al.
Publicado: (2017)

Crystal structure of a 2:1 piroxicam–gentisic acid co-crystal featuring neutral and zwitterionic piroxicam molecules
por: Horstman, Elizabeth M., et al.
Publicado: (2016)

4-(Dimethylamino)pyridinium tribromide: whole molecule disorder of cation and anion
por: Ng, Seik Weng
Publicado: (2009)

Crystal structure of (S)-1-O-tert-butyldiphenylsilylglycerol: eight chiral molecules in a triclinic cell
por: Doboszewski, Bogdan, et al.
Publicado: (2018)

One molecule, three crystal structures: conformational trimorphism of N-[(1S)-1-phenylethyl]benzamide
por: Flores Manuel, Fermin, et al.
Publicado: (2020)

SEABED: Small molEcule activity scanner weB servicE baseD
por: Fenollosa, Carlos, et al.
Publicado: (2015)

Crystal structure of an aryl cyclohexyl nonanoid, an antiproliferative molecule isolated from the spice Myristica malabarica
por: Bauri, Ajoy Kumar, et al.
Publicado: (2016)

Synthesis and crystal structure of a new hybrid organic–inorganic material containing neutral molecules, cations and heptamolybdate anions
por: Sarr, Bougar, et al.
Publicado: (2019)

Obtaining the best results: aspects of data collection, model finalization and interpretation of results in small-molecule crystal-structure determination
por: Linden, Anthony
Publicado: (2020)

Crystal structure of zwitterionic 4-(ammoniomethyl)benzoate: a simple molecule giving rise to a complex supramolecular structure
por: Atria, Ana María, et al.
Publicado: (2014)

Whole-molecule disorder of the Schiff base compound 4-chloro-N-(4-nitrobenzylidene)aniline: crystal structure and Hirshfeld surface analysis
por: Leela, Sundararaman, et al.
Publicado: (2020)

Crystal structure of the insecticide ethiprole (C(13)H(9)Cl(2)F(3)N(4)OS): a case study of whole-molecule configurational disorder
por: Vinaya,, et al.
Publicado: (2023)

2-Acetamido-4,5-dinitrotoluene: a test molecule for the CCDC ‘Blind Structure Prediction Test, 2004’. Corrigendum
por: Watkin, David J., et al.
Publicado: (2012)

Orthorhombic modification of (E)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one: whole molecule disorder
por: Ng, Seik Weng
Publicado: (2009)

6-Isopropyl-3-phenyl-5-(p-tolyloxy)-3H-1,2,3-triazolo[4,5-d]pyrimidin-7(6H)-one: whole-molecule disorder
por: Zeng, Xiao-Hua, et al.
Publicado: (2009)

Synthesis and crystal structure of (1,10-phenanthroline-κ(2) N,N′)[2-(1H-pyrazol-1-yl)phenyl-κ(2) N (2),C (1)]iridium(III) hexafluoridophosphate with an unknown number of solvent molecules
por: Zeng, Juxiang, et al.
Publicado: (2020)

Crystal structure of 5-amino-5′-chloro-6-(4-chlorobenzoyl)-8-nitro-2,3-dihydro-1H-spiro[imidazo[1,2-a]pyridine-7,3′-indolin]-2′-one including an unknown solvent molecule
por: Nagalakshmi, R. A., et al.
Publicado: (2014)

Crystal structure of cis-bis{4-phenyl-1-[(3R)-1,7,7-trimethyl-2-oxobicyclo[2.2.1]heptan-3-ylidene]thiosemicarbazidato-κ(3) O,N (1),S}cadmium(II) with an unknown solvent molecule
por: Nogueira, Vanessa Senna, et al.
Publicado: (2015)

Crystal structure and Hirshfeld surface analysis of mono/bis(aqua-κO)[N-(2-oxidobenzylidene)valinato-κ(3) O,N,O′]copper(II): dimeric Schiff base copper(II) complexes having different numbers of coordinated water molecules
por: Akiyama, Yukihito, et al.
Publicado: (2023)

Crystal and molecular structure of aflatrem
por: Lenta, Bruno N., et al.
Publicado: (2015)

Whole-molecule disordered (E)-2-(1-hydroxy-3-phenylprop-2-en-1-ylidene)-4,5-dimethoxycyclopent-4-ene-1,3-dione isolated from Lindera oxyphylla (Lauraceae)
por: Hosseinzadeh, Masoumeh, et al.
Publicado: (2011)

Channels with ordered water and bipyridine molecules in the porous coordination polymer {[Cu(SiF(6))(C(10)H(8)N(2))(2)]·2C(10)N(2)H(8)·5H(2)O}(n)
por: Aubert, Emmanuel, et al.
Publicado: (2016)

MolMeDB: Molecules on Membranes Database
por: Juračka, Jakub, et al.
Publicado: (2019)

Tris(4,4′-di-tert-butyl-2,2′-bipyridine)(trans-4-tert-butylcyclohexanolato)deca-μ-oxido-heptaoxidoheptavanadium acetonitrile monosolvate including another unknown solvent molecule
por: Kodama, Shintaro, et al.
Publicado: (2020)

The Effects of Riluzole on Cisplatin-induced Ototoxicity
por: Üstün Bezgin, Selin, et al.
Publicado: (2019)

Riluzole: Interstitial pneumonia: case report
Publicado: (2022)

Riluzole as a Neuroprotective Drug for Spinal Cord Injury: From Bench to Bedside
por: Nagoshi, Narihito, et al.
Publicado: (2015)

Riluzole Ameliorates Harmaline-induced Tremor in Rat
por: Shourmasti, Fatemeh Rahimi, et al.
Publicado: (2014)

Stability-indicating Method for the Estimation of Riluzole in Tablets
por: Neeha, T., et al.
Publicado: (2013)

Crystal structure of (2R)-1-[(methylsulfonyl)oxy]propan-2-aminium chloride: a chiral molecular salt
por: Rajegowda, H. R., et al.
Publicado: (2015)

Fluorenonophane chlorobenzene solvate: molecular and crystal structures
por: Dyakonenko, Viktoriya V., et al.
Publicado: (2021)

SigMol: repertoire of quorum sensing signaling molecules in prokaryotes
por: Rajput, Akanksha, et al.
Publicado: (2016)

MolDiscovery: learning mass spectrometry fragmentation of small molecules
por: Cao, Liu, et al.
Publicado: (2021)

N-Succinylaspartic-Acid-Conjugated Riluzole Is a Safe and Potent Colon-Targeted Prodrug of Riluzole against DNBS-Induced Rat Colitis
por: Kim, Jaejeong, et al.
Publicado: (2023)

Riluzole: A neuroprotective drug with potential as a novel anti-cancer agent (Review)
por: Blyufer, Angelina, et al.
Publicado: (2021)

Structural characterization of two benzene-1,2-diamine complexes of zinc chloride: a molecular compound and a co-crystal salt
por: Zick, Patricia L., et al.
Publicado: (2016)

Pharmacological investigation of memory restorative effect of riluzole in mice
por: Rinwa, Puneet, et al.
Publicado: (2012)

Riluzole Stimulates BDNF Release from Human Platelets
por: Türck, Patrick, et al.
Publicado: (2015)

Antitumor Activity and Mechanism Study of Riluzole and Its Derivatives
por: Wu, Xiang-Long, et al.
Publicado: (2020)

Riluzole and Edavarone: The Hope Against Amyotrophic Lateral Sclerosis
por: Rokade, Aditi V, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_06nmiaah5a6o8bqij9gbo032dd