Cargando…
Myocardial global longitudinal strain: An early indicator of cardiac interstitial fibrosis modified by spironolactone, in a unique hypertensive rat model
OBJECTIVES: Is global longitudinal strain (GLS) a more accurate non-invasive measure of histological myocardial fibrosis than left ventricular ejection fraction (LVEF) in a hypertensive rodent model. BACKGROUND: Hypertension results in left ventricular hypertrophy and cardiac dysfunction. Speckle-tr...
Autores principales: | Leader, Catherine J., Moharram, Mohammed, Coffey, Sean, Sammut, Ivan A., Wilkins, Gerard W., Walker, Robert J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690508/ https://www.ncbi.nlm.nih.gov/pubmed/31404095 http://dx.doi.org/10.1371/journal.pone.0220837 |
Ejemplares similares
-
Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat
por: Leader, Catherine J., et al.
Publicado: (2020) -
The effect of spironolactone on cardiac and renal fibrosis following myocardial infarction in established hypertension in the transgenic Cyp1a1Ren2 rat
por: Leader, C. J., et al.
Publicado: (2021) -
Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone
por: Coelho‐Filho, Otavio R., et al.
Publicado: (2014) -
Renal Fibrosis mRNA Classifier: Validation in Experimental Lithium-Induced Interstitial Fibrosis in the Rat Kidney
por: Marti, Hans-Peter, et al.
Publicado: (2016) -
Spironolactone alleviates myocardial fibrosis via inhibition of Ets-1 in mice with experimental autoimmune myocarditis
por: Wang, Wen-Ke, et al.
Publicado: (2022)