Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action

Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) and the nuclear receptor co-repressor1 (NCoR1) are paralogs and regulate nuclear receptor (NR) function through the recruitment of a multiprotein complex that includes histone deacetylase activity. Previous genetic strategies which...

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Detalles Bibliográficos
Autores principales: Shimizu, Hiroaki, Lu, Yu, Vella, Kristen R., Damilano, Federico, Astapova, Inna, Amano, Izuki, Ritter, Megan, Gallop, Molly R., Rosenzweig, Anthony N., Cohen, Ronald N., Hollenberg, Anthony N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690520/
https://www.ncbi.nlm.nih.gov/pubmed/31404087
http://dx.doi.org/10.1371/journal.pone.0220717

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