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Metabolomic profiling reveals salivary hypotaurine as a potential early detection marker for medication-related osteonecrosis of the jaw

Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse event of bone-modifying agents used to prevent bone complications in cancer patients with bone metastasis. Currently, early treatment is the only way to prevent further progression, as the pathogenesis of MRONJ has not...

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Detalles Bibliográficos
Autores principales: Yatsuoka, Wakako, Ueno, Takao, Miyano, Kanako, Uezono, Yasuhito, Enomoto, Ayame, Kaneko, Miku, Ota, Sana, Soga, Tomoyoshi, Sugimoto, Masahiro, Ushijima, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690531/
https://www.ncbi.nlm.nih.gov/pubmed/31404085
http://dx.doi.org/10.1371/journal.pone.0220712