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Identifying important parameters in the inflammatory process with a mathematical model of immune cell influx and macrophage polarization

In an inflammatory setting, macrophages can be polarized to an inflammatory M1 phenotype or to an anti-inflammatory M2 phenotype, as well as existing on a spectrum between these two extremes. Dysfunction of this phenotypic switch can result in a population imbalance that leads to chronic wounds or d...

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Detalles Bibliográficos
Autores principales: Torres, Marcella, Wang, Jing, Yannie, Paul J., Ghosh, Shobha, Segal, Rebecca A., Reynolds, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690555/
https://www.ncbi.nlm.nih.gov/pubmed/31365522
http://dx.doi.org/10.1371/journal.pcbi.1007172

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