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Identifying important parameters in the inflammatory process with a mathematical model of immune cell influx and macrophage polarization
In an inflammatory setting, macrophages can be polarized to an inflammatory M1 phenotype or to an anti-inflammatory M2 phenotype, as well as existing on a spectrum between these two extremes. Dysfunction of this phenotypic switch can result in a population imbalance that leads to chronic wounds or d...
Autores principales: | Torres, Marcella, Wang, Jing, Yannie, Paul J., Ghosh, Shobha, Segal, Rebecca A., Reynolds, Angela M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690555/ https://www.ncbi.nlm.nih.gov/pubmed/31365522 http://dx.doi.org/10.1371/journal.pcbi.1007172 |
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