Cargando…
Cognition may link cortical IGFBP5 levels with motor function in older adults
Alzheimer’s disease and related disorders (ADRD) may manifest cognitive and non-cognitive phenotypes including motor impairment, suggesting a shared underlying biology. We tested the hypothesis that five cortical proteins identified from a gene network that drives AD and cognitive phenotypes are als...
Autores principales: | Buchman, Aron S., Yu, Lei, Petyuk, Vladislav A., Gaiteri, Chris, Tasaki, Shinya, Blizinsky, Katherine D., Schneider, Julie A., De Jager, Philip L., Bennett, David A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690580/ https://www.ncbi.nlm.nih.gov/pubmed/31404102 http://dx.doi.org/10.1371/journal.pone.0220968 |
Ejemplares similares
-
Genetic risk for Alzheimer’s dementia predicts motor deficits through multi-omic systems in older adults
por: Tasaki, Shinya, et al.
Publicado: (2019) -
Cortical proteins may provide motor resilience in older adults
por: Buchman, Aron S., et al.
Publicado: (2021) -
Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults
por: Zammit, Andrea R., et al.
Publicado: (2022) -
Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics
por: Gaiteri, Chris, et al.
Publicado: (2018) -
Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks
por: Tasaki, Shinya, et al.
Publicado: (2022)