MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition

The NuRD complex contains both chromatin remodeling and histone deacetylase activities. Mice lacking the MTA2 subunit of NuRD show developmental defects in pro-B, pre-B, immature B, and marginal zone B cells, and abnormal germinal center B cell differentiation during immune responses. Mta2 inactivat...

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Detalles Bibliográficos
Autores principales: Lu, Xiangdong, Chu, Chi-Shuen, Fang, Terry, Rayon-Estrada, Violeta, Fang, Fang, Patke, Alina, Qian, Ye, Clarke, Stephen H., Melnick, Ari M., Zhang, Yi, Papavasiliou, F. Nina, Roeder, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690613/
https://www.ncbi.nlm.nih.gov/pubmed/31291582
http://dx.doi.org/10.1016/j.celrep.2019.06.029

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