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Correlation Between MYCN Gene Status and MYCN Protein Expression in Neuroblastoma: A Pilot Study To Propose the Use of MYCN Immunohistochemistry in Limited-Resource Areas
PURPOSE: The most significant adverse risk factor for neuroblastoma (NB) is MYCN gene amplification, which strongly associates with high-risk disease. Fluorescent in situ hybridization (FISH) is considered the best method to evaluate MYCN gene status. However, it requires a laboratory that can perfo...
Autores principales: | Santiago, Teresa, Tarek, Nidale, Boulos, Fouad, Hayes, Caleb, Jeha, Sima, Raimondi, Susana, Rodriguez-Galindo, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Clinical Oncology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690657/ https://www.ncbi.nlm.nih.gov/pubmed/31365300 http://dx.doi.org/10.1200/JGO.19.00135 |
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