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Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth
Human glioblastoma cells are strikingly refractory to ATP-stimulated, P2X7 receptor (P2X7R)-mediated cytotoxicity. To elucidate the mechanistic basis of this feature, we investigated P2X7R-dependent responses in wild type and P2X7R-transfected U138 cells. Mouse GL261 glioma cells were used as an add...
Autores principales: | Bergamin, Letícia Scussel, Capece, Marina, Salaro, Erica, Sarti, Alba Clara, Falzoni, Simonetta, Pereira, Mery Stéfani Leivas, De Bastiani, Marco Antônio, Scholl, Juliete Nathali, Battastini, Ana Maria O., Di Virgilio, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690673/ https://www.ncbi.nlm.nih.gov/pubmed/31448051 http://dx.doi.org/10.18632/oncotarget.27106 |
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