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Dominant role of the α-chain in rejection of tumor cells bearing a specific alloantigen in TCRα transgenic mice and in in vitro experiments

Both TCRα and TCRβ types of T-cell receptors contribute to antigen recognition. However, some TCRs have chain centricity, which means that either the α-chain or the β-chain dictates the peptide–MHC complex specificity. Most earlier reports investigated the role of well-studied β-chains in antigen re...

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Detalles Bibliográficos
Autores principales:	Zamkova, Maria, Kalinina, Anastasiya, Silaeva, Yuliya, Persiyantseva, Nadezhda, Bruter, Alexandra, Deikin, Alexey, Khromykh, Ludmila, Kazansky, Dmitry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690675/ https://www.ncbi.nlm.nih.gov/pubmed/31448049 http://dx.doi.org/10.18632/oncotarget.27093

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