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Data on the stability of Prx1-associated snRNAs and mRNAs
This data set is related to the research article entitled “Peroxiredoxin 1 post-transcriptionally regulates snoRNA expression” (Kim et al., 2019). It demonstrates that peroxiredoxin 1 (Prx1) increases the stability of Prx1-associated small nuclear RNAs (snRNAs) and mRNAs. We overexpressed Prx1 in SN...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690714/ https://www.ncbi.nlm.nih.gov/pubmed/31417951 http://dx.doi.org/10.1016/j.dib.2019.104309 |
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author | Kim, Eun-Kyung Ahn, Sung-Min Jang, Ho Hee |
author_facet | Kim, Eun-Kyung Ahn, Sung-Min Jang, Ho Hee |
author_sort | Kim, Eun-Kyung |
collection | PubMed |
description | This data set is related to the research article entitled “Peroxiredoxin 1 post-transcriptionally regulates snoRNA expression” (Kim et al., 2019). It demonstrates that peroxiredoxin 1 (Prx1) increases the stability of Prx1-associated small nuclear RNAs (snRNAs) and mRNAs. We overexpressed Prx1 in SNU484 and HeLa cells, which were then treated with Actinomycin D (ActD) to inhibit transcription. After that, we measured the levels of Prx1-associated snRNAs and mRNAs using qPCR analysis. |
format | Online Article Text |
id | pubmed-6690714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-66907142019-08-15 Data on the stability of Prx1-associated snRNAs and mRNAs Kim, Eun-Kyung Ahn, Sung-Min Jang, Ho Hee Data Brief Biochemistry, Genetics and Molecular Biology This data set is related to the research article entitled “Peroxiredoxin 1 post-transcriptionally regulates snoRNA expression” (Kim et al., 2019). It demonstrates that peroxiredoxin 1 (Prx1) increases the stability of Prx1-associated small nuclear RNAs (snRNAs) and mRNAs. We overexpressed Prx1 in SNU484 and HeLa cells, which were then treated with Actinomycin D (ActD) to inhibit transcription. After that, we measured the levels of Prx1-associated snRNAs and mRNAs using qPCR analysis. Elsevier 2019-07-25 /pmc/articles/PMC6690714/ /pubmed/31417951 http://dx.doi.org/10.1016/j.dib.2019.104309 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Biochemistry, Genetics and Molecular Biology Kim, Eun-Kyung Ahn, Sung-Min Jang, Ho Hee Data on the stability of Prx1-associated snRNAs and mRNAs |
title | Data on the stability of Prx1-associated snRNAs and mRNAs |
title_full | Data on the stability of Prx1-associated snRNAs and mRNAs |
title_fullStr | Data on the stability of Prx1-associated snRNAs and mRNAs |
title_full_unstemmed | Data on the stability of Prx1-associated snRNAs and mRNAs |
title_short | Data on the stability of Prx1-associated snRNAs and mRNAs |
title_sort | data on the stability of prx1-associated snrnas and mrnas |
topic | Biochemistry, Genetics and Molecular Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690714/ https://www.ncbi.nlm.nih.gov/pubmed/31417951 http://dx.doi.org/10.1016/j.dib.2019.104309 |
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