Cargando…

Data on the stability of Prx1-associated snRNAs and mRNAs

This data set is related to the research article entitled “Peroxiredoxin 1 post-transcriptionally regulates snoRNA expression” (Kim et al., 2019). It demonstrates that peroxiredoxin 1 (Prx1) increases the stability of Prx1-associated small nuclear RNAs (snRNAs) and mRNAs. We overexpressed Prx1 in SN...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun-Kyung, Ahn, Sung-Min, Jang, Ho Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690714/
https://www.ncbi.nlm.nih.gov/pubmed/31417951
http://dx.doi.org/10.1016/j.dib.2019.104309
_version_ 1783443231888900096
author Kim, Eun-Kyung
Ahn, Sung-Min
Jang, Ho Hee
author_facet Kim, Eun-Kyung
Ahn, Sung-Min
Jang, Ho Hee
author_sort Kim, Eun-Kyung
collection PubMed
description This data set is related to the research article entitled “Peroxiredoxin 1 post-transcriptionally regulates snoRNA expression” (Kim et al., 2019). It demonstrates that peroxiredoxin 1 (Prx1) increases the stability of Prx1-associated small nuclear RNAs (snRNAs) and mRNAs. We overexpressed Prx1 in SNU484 and HeLa cells, which were then treated with Actinomycin D (ActD) to inhibit transcription. After that, we measured the levels of Prx1-associated snRNAs and mRNAs using qPCR analysis.
format Online
Article
Text
id pubmed-6690714
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-66907142019-08-15 Data on the stability of Prx1-associated snRNAs and mRNAs Kim, Eun-Kyung Ahn, Sung-Min Jang, Ho Hee Data Brief Biochemistry, Genetics and Molecular Biology This data set is related to the research article entitled “Peroxiredoxin 1 post-transcriptionally regulates snoRNA expression” (Kim et al., 2019). It demonstrates that peroxiredoxin 1 (Prx1) increases the stability of Prx1-associated small nuclear RNAs (snRNAs) and mRNAs. We overexpressed Prx1 in SNU484 and HeLa cells, which were then treated with Actinomycin D (ActD) to inhibit transcription. After that, we measured the levels of Prx1-associated snRNAs and mRNAs using qPCR analysis. Elsevier 2019-07-25 /pmc/articles/PMC6690714/ /pubmed/31417951 http://dx.doi.org/10.1016/j.dib.2019.104309 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Biochemistry, Genetics and Molecular Biology
Kim, Eun-Kyung
Ahn, Sung-Min
Jang, Ho Hee
Data on the stability of Prx1-associated snRNAs and mRNAs
title Data on the stability of Prx1-associated snRNAs and mRNAs
title_full Data on the stability of Prx1-associated snRNAs and mRNAs
title_fullStr Data on the stability of Prx1-associated snRNAs and mRNAs
title_full_unstemmed Data on the stability of Prx1-associated snRNAs and mRNAs
title_short Data on the stability of Prx1-associated snRNAs and mRNAs
title_sort data on the stability of prx1-associated snrnas and mrnas
topic Biochemistry, Genetics and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690714/
https://www.ncbi.nlm.nih.gov/pubmed/31417951
http://dx.doi.org/10.1016/j.dib.2019.104309
work_keys_str_mv AT kimeunkyung dataonthestabilityofprx1associatedsnrnasandmrnas
AT ahnsungmin dataonthestabilityofprx1associatedsnrnasandmrnas
AT janghohee dataonthestabilityofprx1associatedsnrnasandmrnas