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Chloroquine and mefloquine resistance profiles are not related to the circumsporozoite protein (CSP) VK210 subtypes in field isolates of Plasmodium vivax from Manaus, Brazilian Amazon
BACKGROUND: The central repetitive region (CRR) of the Plasmodium vivax circumsporozoite surface protein (CSP) is composed of a repetitive sequence that is characterised by three variants: VK210, VK247 and P. vivax-like. The most important challenge in the treatment of P. vivax infection is the poss...
Autores principales: | Pratt-Riccio, Lilian Rose, Baptista, Bárbara de Oliveira, Torres, Vanessa Rodrigues, Bianco-Junior, Cesare, Perce-Da-Silva, Daiana de Souza, Riccio, Evelyn Kety Pratt, Lima-Junior, Josué da Costa, Totino, Paulo Renato Rivas, Cassiano, Gustavo Capatti, Storti-Melo, Luciane Moreno, Machado, Ricardo Luiz Dantas, de Oliveira-Ferreira, Joseli, Banic, Dalma Maria, Carvalho, Leonardo José de Moura, Daniel-Ribeiro, Cláudio Tadeu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690721/ https://www.ncbi.nlm.nih.gov/pubmed/31411308 http://dx.doi.org/10.1590/0074-02760190054 |
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