Proteomics reveals NNMT as a master metabolic regulator of cancer associated fibroblasts

High grade serous carcinoma (HGSC) has a poor prognosis primarily due to its early dissemination throughout the abdominal cavity. Genomic and proteomic approaches have provided snapshots of the proteogenomics of ovarian cancer (OvCa)(1,2), but a systematic examination of both the tumor and stromal c...

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Detalles Bibliográficos
Autores principales: Eckert, Mark A., Coscia, Fabian, Chryplewicz, Agnieszka, Chang, Jae Won, Hernandez, Kyle M., Pan, Shawn, Tienda, Samantha M., Nahotko, Dominik A., Li, Gang, Blaženović, Ivana, Lastra, Ricardo R., Curtis, Marion, Yamada, S. Diane, Perets, Ruth, McGregor, Stephanie M., Andrade, Jorge, Fiehn, Oliver, Moellering, Raymond E., Mann, Matthias, Lengyel, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690743/
https://www.ncbi.nlm.nih.gov/pubmed/31043742
http://dx.doi.org/10.1038/s41586-019-1173-8

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