Melatonin MT2 receptor agonist IIK-7 produces antinociception by modulation of ROS and suppression of spinal microglial activation in neuropathic pain rats

BACKGROUND: In recent years, several melatonin (MLT) receptor agonists have been approved by FDA for the treatment of sleep disorders and depression. Very few studies have shed light on their efficacy against neuropathic pain (NP). IIK-7 is an MT-2 agonist known to promote sleep. Whether IIK-7 suppr...

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Detalles Bibliográficos
Autores principales: Kuthati, Yaswanth, Goutham Davuluri, Venkata Naga, Yang, Chih-Ping, Chang, Hsiao-Cheng, Chang, Chih-Peng, Wong, Chih Shung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690853/
https://www.ncbi.nlm.nih.gov/pubmed/31496789
http://dx.doi.org/10.2147/JPR.S214671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690853/
https://www.ncbi.nlm.nih.gov/pubmed/31496789
http://dx.doi.org/10.2147/JPR.S214671

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