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Atorvastatin increases the production of proinflammatory cytokines and decreases the survival of Escherichia coli-infected mice
To assess whether the immunosuppressive effects of atorvastatin outweigh its antibacterial ones in an infection, mice were infected with Escherichia coli and administered atorvastatin; survival rates were then monitored. Mice treated with atorvastatin post-infection showed a remarkable decrease in t...
Autores principales: | Hussein, Hadi M., Al-Khoury, Diva Kalash, Abdelnoor, Alexander M., Rahal, Elias A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690901/ https://www.ncbi.nlm.nih.gov/pubmed/31406240 http://dx.doi.org/10.1038/s41598-019-48282-2 |
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