SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway

SOCS5 is a member of the suppressor of cytokine signaling (SOCS) protein family with important yet incompletely understood biological functions in cancer. In hepatocellular carcinoma (HCC), controversial tumor-promoting and tumor-suppressive roles of SOCS5 have been reported. Our study aims to unrav...

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Detalles Bibliográficos
Autores principales: Zhang, Mao, Liu, Shihai, Chua, Mei-Sze, Li, Haoran, Luo, Dingan, Wang, Sheng, Zhang, Shun, Han, Bing, Sun, Chuandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690952/
https://www.ncbi.nlm.nih.gov/pubmed/31406106
http://dx.doi.org/10.1038/s41419-019-1856-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690952/
https://www.ncbi.nlm.nih.gov/pubmed/31406106
http://dx.doi.org/10.1038/s41419-019-1856-y

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