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SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway
SOCS5 is a member of the suppressor of cytokine signaling (SOCS) protein family with important yet incompletely understood biological functions in cancer. In hepatocellular carcinoma (HCC), controversial tumor-promoting and tumor-suppressive roles of SOCS5 have been reported. Our study aims to unrav...
Autores principales: | Zhang, Mao, Liu, Shihai, Chua, Mei-Sze, Li, Haoran, Luo, Dingan, Wang, Sheng, Zhang, Shun, Han, Bing, Sun, Chuandong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690952/ https://www.ncbi.nlm.nih.gov/pubmed/31406106 http://dx.doi.org/10.1038/s41419-019-1856-y |
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