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Staurosporine from Streptomyces sanyensis activates Programmed Cell Death in Acanthamoeba via the mitochondrial pathway and presents low in vitro cytotoxicity levels in a macrophage cell line
Recently, the search for novel therapeutic agents against Acanthamoeba species has been focused on the evaluation of natural resources. Among them, marine microorganisms have risen as a source of bioactive compounds with the advantage of the ability to obtain unlimited and constant amounts of the co...
Autores principales: | Cartuche, Luis, Sifaoui, Ines, Cruz, Darío, Reyes-Batlle, María, López-Arencibia, Atteneri, Javier Fernández, José, Díaz-Marrero, Ana R., Piñero, José E., Lorenzo-Morales, Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690954/ https://www.ncbi.nlm.nih.gov/pubmed/31406269 http://dx.doi.org/10.1038/s41598-019-48261-7 |
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