Cancer Testis Antigen Promotes Triple Negative Breast Cancer Metastasis and is Traceable in the Circulating Extracellular Vesicles

Triple negative breast cancer (TNBC) has poor survival, exhibits rapid metastases, lacks targeted therapies and reliable prognostic markers. Here, we examined metastasis promoting role of cancer testis antigen SPANXB1 in TNBC and its utility as a therapeutic target and prognostic biomarker. Expressi...

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Detalles Bibliográficos
Autores principales: Kannan, Anbarasu, Philley, Julie V., Hertweck, Kate L., Ndetan, Harrison, Singh, Karan P., Sivakumar, Subramanium, Wells, Robert B., Vadlamudi, Ratna K., Dasgupta, Santanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690992/
https://www.ncbi.nlm.nih.gov/pubmed/31406142
http://dx.doi.org/10.1038/s41598-019-48064-w

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