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CYLD dysregulation in pathogenesis of sporadic inclusion body myositis

Sporadic inclusion body myositis (sIBM) is the most commonly acquired myopathy in middle-aged and elderly people. The muscle histology is characterized by both inflammation and degeneration, including sarcoplasmic aggregation of TDP-43. Cylindromatosis (CYLD) is a deubiquitinating enzyme that target...

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Detalles Bibliográficos
Autores principales: Yamashita, Satoshi, Matsuo, Yoshimasa, Tawara, Nozomu, Hara, Kentaro, Yamamoto, Masanori, Nishikami, Tomo, Kawakami, Kensuke, Zhang, Xiao, Zhang, Ziwei, Doki, Tsukasa, Ando, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690995/
https://www.ncbi.nlm.nih.gov/pubmed/31406156
http://dx.doi.org/10.1038/s41598-019-48115-2