Direct Access to Substituted 4-CF(3) β-Lactams at the C-3 Position

Mono- and disubstituted 4-CF(3) β-lactams at the C-3 position have been obtained stereoselectively under basic conditions. A wide range of function such as alcohols, alkyls, aryls, esters, and double and triple bonds have been introduced.

Detalles Bibliográficos
Autores principales: Skibińska, Monika, Kaźmierczak, Marcin, Milcent, Thierry, Cytlak, Tomasz, Koroniak, Henryk, Crousse, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691124/
https://www.ncbi.nlm.nih.gov/pubmed/31448256
http://dx.doi.org/10.3389/fchem.2019.00526
Descripción
Sumario:Mono- and disubstituted 4-CF(3) β-lactams at the C-3 position have been obtained stereoselectively under basic conditions. A wide range of function such as alcohols, alkyls, aryls, esters, and double and triple bonds have been introduced.

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