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Genetic Silencing of Fatty Acid Desaturases Modulates α-Synuclein Toxicity and Neuronal Loss in Parkinson-Like Models of C. elegans

The molecular basis of Parkinson’s disease (PD) is currently unknown. There is increasing evidence that fat metabolism is at the crossroad of key molecular pathways associated with the pathophysiology of PD. Fatty acid desaturases catalyze synthesis of saturated fatty acids from monounsaturated fatt...

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Detalles Bibliográficos
Autores principales:	Maulik, Malabika, Mitra, Swarup, Basmayor, Ajiel Mae, Lu, Brianna, Taylor, Barbara E., Bult-Ito, Abel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691153/ https://www.ncbi.nlm.nih.gov/pubmed/31447665 http://dx.doi.org/10.3389/fnagi.2019.00207

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