17β-Estradiol Regulates Glucose Metabolism and Insulin Secretion in Rat Islet β Cells Through GPER and Akt/mTOR/GLUT2 Pathway

Aims: To explore the molecular mechanism by which 17β-estradiol (estrogen 2, E2) regulates glucose transporter 2 (GLUT2) and insulin secretion in islet β cells through G protein-coupled estrogen receptor (GPER) via Akt/mTOR pathway. Methods: SPF-grade SD male rats were used to establish an in vivo t...

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Detalles Bibliográficos
Autores principales: Bian, Che, Bai, Bowen, Gao, Qian, Li, Siyi, Zhao, Yuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691154/
https://www.ncbi.nlm.nih.gov/pubmed/31447779
http://dx.doi.org/10.3389/fendo.2019.00531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691154/
https://www.ncbi.nlm.nih.gov/pubmed/31447779
http://dx.doi.org/10.3389/fendo.2019.00531

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