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Biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients

BACKGROUND: Hospital readmissions of patients with cirrhosis is a current problem in China. This study aims to estimate the readmission rate at one year after discharge and to identify associated risk factors of hospital readmission. METHODS: Between January 2012 and December 2015, 3,402 patients ad...

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Autores principales: Dai, Jingyi, Zhao, Jun, Du, Yingrong, McNeil, Edward B, Chongsuvivatwong, Virasakdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691191/
https://www.ncbi.nlm.nih.gov/pubmed/31496713
http://dx.doi.org/10.2147/TCRM.S203883
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author Dai, Jingyi
Zhao, Jun
Du, Yingrong
McNeil, Edward B
Chongsuvivatwong, Virasakdi
author_facet Dai, Jingyi
Zhao, Jun
Du, Yingrong
McNeil, Edward B
Chongsuvivatwong, Virasakdi
author_sort Dai, Jingyi
collection PubMed
description BACKGROUND: Hospital readmissions of patients with cirrhosis is a current problem in China. This study aims to estimate the readmission rate at one year after discharge and to identify associated risk factors of hospital readmission. METHODS: Between January 2012 and December 2015, 3,402 patients admitted with cirrhosis were included in the study. The primary outcome was one-year inpatient readmission. Principal components analysis was conducted on the laboratory test indicators to reduce the number of dimensions. Univariate and multivariate analyses were performed using clinical and demographic data to identify independent associated factors of readmission within one year. The odds ratio (OR) and 95% confidence interval were used to assess the strength of association for each factor. RESULTS: Two dimensions, namely “liver function” and “renal function”, were revealed. Patients with a longer length of stay in the index admission (OR: 1.03; 95% CI: 1.03–1.04) and a higher dimension score of liver function (OR: 1.09; 95% CI: 1.05–1.13) were more likely to be readmitted within one-year. Older patients had a significantly higher odds of one-year readmission than younger patients (OR: 1.61; 95% CI: 1.22–2.11), patients who were married had a higher odds than those who were single (OR: 1.62; 95% CI: 1.12–2.36), and patients with hepatitis C virus were more likely to be readmitted within one year than patients with hepatitis B virus (OR: 1.51; 95% CI: 1.19–1.91). CONCLUSION: Biomarkers and sociodemographic factors can identify patients at high risk for readmission within one year. Our data indicates the need to emphasize proper liver care to older patients who have been hospitalized for a long time.
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spelling pubmed-66911912019-09-06 Biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients Dai, Jingyi Zhao, Jun Du, Yingrong McNeil, Edward B Chongsuvivatwong, Virasakdi Ther Clin Risk Manag Original Research BACKGROUND: Hospital readmissions of patients with cirrhosis is a current problem in China. This study aims to estimate the readmission rate at one year after discharge and to identify associated risk factors of hospital readmission. METHODS: Between January 2012 and December 2015, 3,402 patients admitted with cirrhosis were included in the study. The primary outcome was one-year inpatient readmission. Principal components analysis was conducted on the laboratory test indicators to reduce the number of dimensions. Univariate and multivariate analyses were performed using clinical and demographic data to identify independent associated factors of readmission within one year. The odds ratio (OR) and 95% confidence interval were used to assess the strength of association for each factor. RESULTS: Two dimensions, namely “liver function” and “renal function”, were revealed. Patients with a longer length of stay in the index admission (OR: 1.03; 95% CI: 1.03–1.04) and a higher dimension score of liver function (OR: 1.09; 95% CI: 1.05–1.13) were more likely to be readmitted within one-year. Older patients had a significantly higher odds of one-year readmission than younger patients (OR: 1.61; 95% CI: 1.22–2.11), patients who were married had a higher odds than those who were single (OR: 1.62; 95% CI: 1.12–2.36), and patients with hepatitis C virus were more likely to be readmitted within one year than patients with hepatitis B virus (OR: 1.51; 95% CI: 1.19–1.91). CONCLUSION: Biomarkers and sociodemographic factors can identify patients at high risk for readmission within one year. Our data indicates the need to emphasize proper liver care to older patients who have been hospitalized for a long time. Dove 2019-08-08 /pmc/articles/PMC6691191/ /pubmed/31496713 http://dx.doi.org/10.2147/TCRM.S203883 Text en © 2019 Dai et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Dai, Jingyi
Zhao, Jun
Du, Yingrong
McNeil, Edward B
Chongsuvivatwong, Virasakdi
Biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients
title Biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients
title_full Biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients
title_fullStr Biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients
title_full_unstemmed Biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients
title_short Biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients
title_sort biomarkers and sociodemographic factors predicting one-year readmission among liver cirrhosis patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691191/
https://www.ncbi.nlm.nih.gov/pubmed/31496713
http://dx.doi.org/10.2147/TCRM.S203883
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