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Silencing RRM2 inhibits multiple myeloma by targeting the Wnt/β-catenin signaling pathway

Ribonucleotide reductase M2 (RRM2) is one of the two subunits that comprise ribonucleotide reductase (RR), the enzyme that catalyzes the conversion of ribonucleotide 5′-diphosphates into 2′-deoxyribonucleotides, which are required for DNA synthesis. RRM2 is a stress response factor important for the...

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Detalles Bibliográficos
Autores principales:	Liu, Xia, Peng, Jiamin, Zhou, Yayun, Xie, Bei, Wang, Jianchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691237/ https://www.ncbi.nlm.nih.gov/pubmed/31322175 http://dx.doi.org/10.3892/mmr.2019.10465

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