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Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series

Ovarian Sex Cord Stromal Tumors (SCST) are a rare disease carrying a good prognosis. They generally affect young women; therefore fertility preservation is a critical issue. Fertility Sparing Surgery (FSS) showed promising results in both oncologic safety and fertility preservation. A retrospective...

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Autores principales: Ghalleb, Montassar, Bouzaiene, Hatem, Sghaier, Sarah, Bouaziz, Hanen, Hechiche, Monia, Hassouna, Jamel Ben, Rahal, Khaled
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691291/
https://www.ncbi.nlm.nih.gov/pubmed/31447979
http://dx.doi.org/10.11604/pamj.2018.31.221.15531
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author Ghalleb, Montassar
Bouzaiene, Hatem
Sghaier, Sarah
Bouaziz, Hanen
Hechiche, Monia
Hassouna, Jamel Ben
Rahal, Khaled
author_facet Ghalleb, Montassar
Bouzaiene, Hatem
Sghaier, Sarah
Bouaziz, Hanen
Hechiche, Monia
Hassouna, Jamel Ben
Rahal, Khaled
author_sort Ghalleb, Montassar
collection PubMed
description Ovarian Sex Cord Stromal Tumors (SCST) are a rare disease carrying a good prognosis. They generally affect young women; therefore fertility preservation is a critical issue. Fertility Sparing Surgery (FSS) showed promising results in both oncologic safety and fertility preservation. A retrospective case series involving 9 patients diagnosed with SCST and treated with fertility sparing surgery at our institution was conducted between January 2000 and May 2015. The median age was 24 years old (10 to 39). The main clinical manifestation was pelvic pain seen in seven patients. Five patients complained about menstrual cycle disorders. The nine patients went through fertility sparing surgery; seven had conservative staging and the other two had a unilateral salpingo-oophorectomy. Three patients out of nine had a pelvic unilateral lymphadenectomy. Two patients received adjuvant chemotherapy. Only two patients presented locoregional recurrence that occurred respectively after 7 and 192 months. The treatment combined chemotherapy and surgery based on mass resection. One patient achieved a natural pregnancy after the treatment. FSS seems to be a suitable approach for SCST. However, more case series and meta-analysis should be conducted.
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spelling pubmed-66912912019-08-23 Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series Ghalleb, Montassar Bouzaiene, Hatem Sghaier, Sarah Bouaziz, Hanen Hechiche, Monia Hassouna, Jamel Ben Rahal, Khaled Pan Afr Med J Case Series Ovarian Sex Cord Stromal Tumors (SCST) are a rare disease carrying a good prognosis. They generally affect young women; therefore fertility preservation is a critical issue. Fertility Sparing Surgery (FSS) showed promising results in both oncologic safety and fertility preservation. A retrospective case series involving 9 patients diagnosed with SCST and treated with fertility sparing surgery at our institution was conducted between January 2000 and May 2015. The median age was 24 years old (10 to 39). The main clinical manifestation was pelvic pain seen in seven patients. Five patients complained about menstrual cycle disorders. The nine patients went through fertility sparing surgery; seven had conservative staging and the other two had a unilateral salpingo-oophorectomy. Three patients out of nine had a pelvic unilateral lymphadenectomy. Two patients received adjuvant chemotherapy. Only two patients presented locoregional recurrence that occurred respectively after 7 and 192 months. The treatment combined chemotherapy and surgery based on mass resection. One patient achieved a natural pregnancy after the treatment. FSS seems to be a suitable approach for SCST. However, more case series and meta-analysis should be conducted. The African Field Epidemiology Network 2018-12-05 /pmc/articles/PMC6691291/ /pubmed/31447979 http://dx.doi.org/10.11604/pamj.2018.31.221.15531 Text en © Montassar Ghalleb et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Ghalleb, Montassar
Bouzaiene, Hatem
Sghaier, Sarah
Bouaziz, Hanen
Hechiche, Monia
Hassouna, Jamel Ben
Rahal, Khaled
Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
title Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
title_full Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
title_fullStr Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
title_full_unstemmed Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
title_short Fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
title_sort fertility sparing surgery for ovarian sex cord stromal tumors: a nine case series
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691291/
https://www.ncbi.nlm.nih.gov/pubmed/31447979
http://dx.doi.org/10.11604/pamj.2018.31.221.15531
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