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Breaking the paradigm: Dr Insight empowers signature-free, enhanced drug repurposing
MOTIVATION: Transcriptome-based computational drug repurposing has attracted considerable interest by bringing about faster and more cost-effective drug discovery. Nevertheless, key limitations of the current drug connectivity-mapping paradigm have been long overlooked, including the lack of effecti...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691331/ https://www.ncbi.nlm.nih.gov/pubmed/30624606 http://dx.doi.org/10.1093/bioinformatics/btz006 |