Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development

Rationale: Cdc42 is a Rho GTPase that regulates diverse cellular functions. Here, we used genetic techniques to investigate the role of Cdc42 in epidermal development and epidermal barrier formation. Methods: Keratinocyte-restricted Cdc42 knockout mice were generated with the Cre-LoxP system under t...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Wang, Xueer, Guo, Fukun, Jia, Qin, Liu, Nuyun, Chen, Yinghua, Yan, Yuan, Huang, Mianbo, Tang, Huiyi, Deng, Ying, Huang, Simin, Zhou, Zhitao, Zhang, Lu, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691388/
https://www.ncbi.nlm.nih.gov/pubmed/31410202
http://dx.doi.org/10.7150/thno.34014

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