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High-speed crystal detection and characterization using a fast-readout detector

A novel raster-scanning method combining continuous sample translation with the fast readout of a Pilatus P6M detector has been developed on microfocus beamline I24 at Diamond Light Source. This fast grid-scan tool allows the rapid evaluation of large sample volumes without the need to increase the...

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Autores principales: Aishima, Jun, Owen, Robin L., Axford, Danny, Shepherd, Emma, Winter, Graeme, Levik, Karl, Gibbons, Paul, Ashton, Alun, Evans, Gwyndaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691516/
https://www.ncbi.nlm.nih.gov/pubmed/20823554
http://dx.doi.org/10.1107/S0907444910028192
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author Aishima, Jun
Owen, Robin L.
Axford, Danny
Shepherd, Emma
Winter, Graeme
Levik, Karl
Gibbons, Paul
Ashton, Alun
Evans, Gwyndaf
author_facet Aishima, Jun
Owen, Robin L.
Axford, Danny
Shepherd, Emma
Winter, Graeme
Levik, Karl
Gibbons, Paul
Ashton, Alun
Evans, Gwyndaf
author_sort Aishima, Jun
collection PubMed
description A novel raster-scanning method combining continuous sample translation with the fast readout of a Pilatus P6M detector has been developed on microfocus beamline I24 at Diamond Light Source. This fast grid-scan tool allows the rapid evaluation of large sample volumes without the need to increase the beam size at the sample through changes in beamline hardware. A slow version is available for slow-readout detectors. Examples of grid-scan use in centring optically invisible samples and in detecting and characterizing numerous microcrystals on a mesh-like holder illustrate the most common applications of the grid scan now in routine use on I24.
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spelling pubmed-66915162019-08-15 High-speed crystal detection and characterization using a fast-readout detector Aishima, Jun Owen, Robin L. Axford, Danny Shepherd, Emma Winter, Graeme Levik, Karl Gibbons, Paul Ashton, Alun Evans, Gwyndaf Acta Crystallogr D Biol Crystallogr Short Communications A novel raster-scanning method combining continuous sample translation with the fast readout of a Pilatus P6M detector has been developed on microfocus beamline I24 at Diamond Light Source. This fast grid-scan tool allows the rapid evaluation of large sample volumes without the need to increase the beam size at the sample through changes in beamline hardware. A slow version is available for slow-readout detectors. Examples of grid-scan use in centring optically invisible samples and in detecting and characterizing numerous microcrystals on a mesh-like holder illustrate the most common applications of the grid scan now in routine use on I24. International Union of Crystallography 2010-09-01 2010-08-13 /pmc/articles/PMC6691516/ /pubmed/20823554 http://dx.doi.org/10.1107/S0907444910028192 Text en © Aishima et al. 2010 http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/4.0/
spellingShingle Short Communications
Aishima, Jun
Owen, Robin L.
Axford, Danny
Shepherd, Emma
Winter, Graeme
Levik, Karl
Gibbons, Paul
Ashton, Alun
Evans, Gwyndaf
High-speed crystal detection and characterization using a fast-readout detector
title High-speed crystal detection and characterization using a fast-readout detector
title_full High-speed crystal detection and characterization using a fast-readout detector
title_fullStr High-speed crystal detection and characterization using a fast-readout detector
title_full_unstemmed High-speed crystal detection and characterization using a fast-readout detector
title_short High-speed crystal detection and characterization using a fast-readout detector
title_sort high-speed crystal detection and characterization using a fast-readout detector
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691516/
https://www.ncbi.nlm.nih.gov/pubmed/20823554
http://dx.doi.org/10.1107/S0907444910028192
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