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Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection

Background: Although, in theory, valve-sparing aortic root replacement (David procedure) is an ideal surgical option for acute aortic dissection type A (AADA) it is usually not regarded as the first-choice treatment due to the emergency setting and the relative complexity of the procedure. Here, we...

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Autores principales: Aubin, Hug, Akhyari, Payam, Rellecke, Philipp, Pawlitza, Christina, Petrov, George, Lichtenberg, Artur, Kamiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691777/
https://www.ncbi.nlm.nih.gov/pubmed/31448282
http://dx.doi.org/10.3389/fsurg.2019.00046
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author Aubin, Hug
Akhyari, Payam
Rellecke, Philipp
Pawlitza, Christina
Petrov, George
Lichtenberg, Artur
Kamiya, Hiroyuki
author_facet Aubin, Hug
Akhyari, Payam
Rellecke, Philipp
Pawlitza, Christina
Petrov, George
Lichtenberg, Artur
Kamiya, Hiroyuki
author_sort Aubin, Hug
collection PubMed
description Background: Although, in theory, valve-sparing aortic root replacement (David procedure) is an ideal surgical option for acute aortic dissection type A (AADA) it is usually not regarded as the first-choice treatment due to the emergency setting and the relative complexity of the procedure. Here, we report the results of a consecutive, single-surgeon series of 45 AADA patients with the David procedure as first-choice treatment strategy. Methods and Results: Between September 2009 and July 2013 a total of 49 patients with AADA were consecutively operated by the same surgeon at our institution. The David procedure was the treatment of choice for the proximal aorta unless aortic valve pathology or critical preoperative patient status advocated against it. Median follow-up was 5.0 years (CI95%, 4.0–6.0). Out of the 45 patients included in this study the David procedure was performed in 28 patients (62.2%), while in 17 patients (37.8%) an alternative surgical strategy had to be pursued. Although X-clamping (168.5 ± 41.7 vs. 110.3 ± 51.1 min; p = 0.001), cardiopulmonary bypass (CPB) (245.0 ± 62.4 vs. 211.8 ± 123 min; p = 0.029) and total operation time (383.8 ± 88.5 vs. 312.8 ± 144.8; p = 0.047) were significantly longer in the David-group as compared to the non-David group, there was no difference in major complication rate as well as 30-day (17.9 vs. 23.5%; p = 0.645) and 5-year mortality (28.6 vs. 35.3%) between groups. Conclusions: This small series indicates that the David procedure may be safe and feasible as a primary surgical treatment strategy for AADA.
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spelling pubmed-66917772019-08-23 Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection Aubin, Hug Akhyari, Payam Rellecke, Philipp Pawlitza, Christina Petrov, George Lichtenberg, Artur Kamiya, Hiroyuki Front Surg Surgery Background: Although, in theory, valve-sparing aortic root replacement (David procedure) is an ideal surgical option for acute aortic dissection type A (AADA) it is usually not regarded as the first-choice treatment due to the emergency setting and the relative complexity of the procedure. Here, we report the results of a consecutive, single-surgeon series of 45 AADA patients with the David procedure as first-choice treatment strategy. Methods and Results: Between September 2009 and July 2013 a total of 49 patients with AADA were consecutively operated by the same surgeon at our institution. The David procedure was the treatment of choice for the proximal aorta unless aortic valve pathology or critical preoperative patient status advocated against it. Median follow-up was 5.0 years (CI95%, 4.0–6.0). Out of the 45 patients included in this study the David procedure was performed in 28 patients (62.2%), while in 17 patients (37.8%) an alternative surgical strategy had to be pursued. Although X-clamping (168.5 ± 41.7 vs. 110.3 ± 51.1 min; p = 0.001), cardiopulmonary bypass (CPB) (245.0 ± 62.4 vs. 211.8 ± 123 min; p = 0.029) and total operation time (383.8 ± 88.5 vs. 312.8 ± 144.8; p = 0.047) were significantly longer in the David-group as compared to the non-David group, there was no difference in major complication rate as well as 30-day (17.9 vs. 23.5%; p = 0.645) and 5-year mortality (28.6 vs. 35.3%) between groups. Conclusions: This small series indicates that the David procedure may be safe and feasible as a primary surgical treatment strategy for AADA. Frontiers Media S.A. 2019-08-06 /pmc/articles/PMC6691777/ /pubmed/31448282 http://dx.doi.org/10.3389/fsurg.2019.00046 Text en Copyright © 2019 Aubin, Akhyari, Rellecke, Pawlitza, Petrov, Lichtenberg and Kamiya. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Aubin, Hug
Akhyari, Payam
Rellecke, Philipp
Pawlitza, Christina
Petrov, George
Lichtenberg, Artur
Kamiya, Hiroyuki
Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_full Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_fullStr Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_full_unstemmed Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_short Valve-Sparing Aortic Root Replacement as First-Choice Strategy in Acute Type a Aortic Dissection
title_sort valve-sparing aortic root replacement as first-choice strategy in acute type a aortic dissection
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691777/
https://www.ncbi.nlm.nih.gov/pubmed/31448282
http://dx.doi.org/10.3389/fsurg.2019.00046
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