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AcuD Gene Knockout Attenuates the Virulence of Talaromyces marneffei in a Zebrafish Model

Talaromyces marneffei is the only dimorphic species in its genus and causes a fatal systemic mycosis named talaromycosis. Our previous study indicated that knockdown of AcuD gene (encodes isocitrate lyase of glyoxylate bypass) of T. marneffei by RNA interference approach attenuated the virulence of...

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Detalles Bibliográficos
Autores principales: Feng, Jiao, Chen, Zhiwen, He, Liya, Xiao, Xing, Chen, Chunmei, Chu, Jieming, Mylonakis, Eleftherios, Xi, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691920/
https://www.ncbi.nlm.nih.gov/pubmed/31448141
http://dx.doi.org/10.1080/12298093.2019.1620975