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AcuD Gene Knockout Attenuates the Virulence of Talaromyces marneffei in a Zebrafish Model
Talaromyces marneffei is the only dimorphic species in its genus and causes a fatal systemic mycosis named talaromycosis. Our previous study indicated that knockdown of AcuD gene (encodes isocitrate lyase of glyoxylate bypass) of T. marneffei by RNA interference approach attenuated the virulence of...
Autores principales: | Feng, Jiao, Chen, Zhiwen, He, Liya, Xiao, Xing, Chen, Chunmei, Chu, Jieming, Mylonakis, Eleftherios, Xi, Liyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691920/ https://www.ncbi.nlm.nih.gov/pubmed/31448141 http://dx.doi.org/10.1080/12298093.2019.1620975 |
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