Chromatin interactions reveal novel gene targets for drug repositioning in rheumatic diseases

OBJECTIVES: There is a need to identify effective treatments for rheumatic diseases, and while genetic studies have been successful it is unclear which genes contribute to the disease. Using our existing Capture Hi-C data on three rheumatic diseases, we can identify potential causal genes which are...

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Detalles Bibliográficos
Autores principales: Martin, Paul, Ding, James, Duffus, Kate, Gaddi, Vasanthi Priyadarshini, McGovern, Amanda, Ray-Jones, Helen, Yarwood, Annie, Worthington, Jane, Barton, Anne, Orozco, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Miscellaneous
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691931/
https://www.ncbi.nlm.nih.gov/pubmed/31092410
http://dx.doi.org/10.1136/annrheumdis-2018-214649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691931/
https://www.ncbi.nlm.nih.gov/pubmed/31092410
http://dx.doi.org/10.1136/annrheumdis-2018-214649

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