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Ddc2(ATRIP) promotes Mec1(ATR) activation at RPA-ssDNA tracts

The DNA damage checkpoint response is controlled by the phosphatidylinositol 3-kinase-related kinases (PIKK), including ataxia telangiectasia-mutated (ATM) and ATM and Rad3-related (ATR). ATR forms a complex with its partner ATRIP. In budding yeast, ATR and ATRIP correspond to Mec1 and Ddc2, respect...

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Detalles Bibliográficos
Autores principales:	Biswas, Himadri, Goto, Greicy, Wang, Weibin, Sung, Patrick, Sugimoto, Katsunori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692047/ https://www.ncbi.nlm.nih.gov/pubmed/31369547 http://dx.doi.org/10.1371/journal.pgen.1008294

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