A next generation setup for pre-fractionation of non-denatured proteins reveals diverse albumin proteoforms each carrying several post-translational modifications

Proteomic biomarker search requires the greatest analytical reproducibility and detailed information on altered proteoforms. Our protein pre-fractionation applies orthogonal native chromatography and conserves important features of protein variants such as native molecular weight, charge and major g...

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Detalles Bibliográficos
Autores principales: Rhode, Heidrun, Muckova, Petra, Büchler, Rita, Wendler, Sindy, Tautkus, Bärbel, Vogel, Michaela, Moore, Thomas, Grosskreutz, Julian, Klemm, Andree, Nabity, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692309/
https://www.ncbi.nlm.nih.gov/pubmed/31409882
http://dx.doi.org/10.1038/s41598-019-48278-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692309/
https://www.ncbi.nlm.nih.gov/pubmed/31409882
http://dx.doi.org/10.1038/s41598-019-48278-y

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