Fluoroquinolone heteroresistance in Mycobacterium tuberculosis: detection by genotypic and phenotypic assays in experimentally mixed populations

Heteroresistance - the simultaneous presence of drug-susceptible and -resistant organisms - is common in Mycobacterium tuberculosis. In this study, we aimed to determine the limit of detection (LOD) of genotypic assays to detect gatifloxacin-resistant mutants in experimentally mixed populations. A f...

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Detalles Bibliográficos
Autores principales: Rigouts, L., Miotto, P., Schats, M., Lempens, P., Cabibbe, A. M., Galbiati, S., Lampasona, V., de Rijk, P., Cirillo, D. M., de Jong, B. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692311/
https://www.ncbi.nlm.nih.gov/pubmed/31409849
http://dx.doi.org/10.1038/s41598-019-48289-9

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