Cargando…

Role of TGFβ3-Smads-Sp1 axis in DcR3-mediated immune escape of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a leading cause of tumour-associated mortality worldwide, but no significant improvement in treating HCC has been reported with currently available systemic therapies. Immunotherapy represents a new frontier in tumour therapy. Therefore, the immunobiology of hepatoc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Hui-fang, Liu, Yan-ping, Liu, Ding-li, Ma, Yi-dan, Hu, Zhi-yan, Wang, Xiao-yan, Gu, Chuan-sha, Zhong, Yan, Long, Ting, Kan, He-ping, Li, Zu-guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692328/ https://www.ncbi.nlm.nih.gov/pubmed/31409774 http://dx.doi.org/10.1038/s41389-019-0152-0

Ejemplares similares

DcR3 induces epithelial-mesenchymal transition through activation of the TGF-β3/SMAD signaling pathway in CRC
por: Liu, Yan-Ping, et al.
Publicado: (2016)

Research Progress of DcR3 in the Diagnosis and Treatment of Sepsis
por: Su, Jingqian, et al.
Publicado: (2023)

Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis
por: Liang, Chaojie, et al.
Publicado: (2017)

TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC
por: Zhong, Mengya, et al.
Publicado: (2021)

Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer’s disease model
por: Liu, Yi-Ling, et al.
Publicado: (2017)

GATA4 and DcR1 methylation in glioblastomas
por: Vaitkienė, Paulina, et al.
Publicado: (2013)

Expression and clinicopathological implication of DcR3 in lung cancer tissues: a tissue microarray study with 365 cases
por: Zhang, Yu, et al.
Publicado: (2016)

Overexpression of DcR3 and Its Significance on Tumor Cell Differentiation and Proliferation in Glioma
por: Huang, Suning, et al.
Publicado: (2014)

DcR3, a new biomarker for sepsis, correlates with infection severity and procalcitonin
por: Gao, Liqin, et al.
Publicado: (2017)

DcR3 combined with hematological traits serves as a valuable biomarker for the diagnosis of cancer metastasis
por: Li, Junxin, et al.
Publicado: (2017)

DcR3 gene polymorphisms are associated with sporadic breast infiltrating ductal carcinoma in Northeast Chinese women
por: Fu, Zhenkun, et al.
Publicado: (2016)

Decoy receptor 3 (DcR3) overexpression predicts the prognosis and pN2 in pancreatic head carcinoma
por: Zhou, Jian, et al.
Publicado: (2014)

Up-regulation of DcR3 in microbial toxins-stimulated HUVECs involves NF-κB signalling
por: Hou, Yanqiang, et al.
Publicado: (2018)

Absolute quantification of DcR3 and GDF15 from human serum by LC-ESI MS
por: Lancrajan, Ioana, et al.
Publicado: (2015)

LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation
por: Cao, Feng, et al.
Publicado: (2019)

Significance of decoy receptor 3 (Dcr3) and external-signal regulated kinase 1/2 (Erk1/2) in gastric cancer
por: Yang, Donghai, et al.
Publicado: (2012)

The Network of Pro-Inflammatory Factors CD147, DcR3, and IL33 in the Development of Kawasaki Disease
por: Qi, Yanqi, et al.
Publicado: (2021)

Decoy Receptor 3 (DcR3) as a Biomarker of Tumor Deterioration in Female Reproductive Cancers: A Meta-Analysis
por: Jiang, Mengtong, et al.
Publicado: (2016)

Membrane expression of TRAIL receptors DR4, DR5, DcR1 and DcR2 in the normal endometrium, atypical endometrial hyperplasia and endometrioid adenocarcinoma: a tissue microarray study
por: Gottwald, Leszek, et al.
Publicado: (2013)

Huiyang Shengji Extract Improve Chronic Nonhealing Cutaneous through the TGF-β1/Smad3 Signaling Pathway
por: Lin, Yan, et al.
Publicado: (2021)

‘Decoy’ and ‘non-decoy’ functions of DcR3 promote malignant potential in human malignant fibrous histiocytoma cells
por: TODA, MITSUNORI, et al.
Publicado: (2013)

Endoscopic DCR vs External DCR: What's Best in the Acute Setting?
por: Amadi, Arash J.
Publicado: (2017)

Dendritic cells engineered to secrete anti-DcR3 antibody augment cytotoxic T lymphocyte response against pancreatic cancer in vitro
por: Chen, Jiang, et al.
Publicado: (2017)

Specific elevation of DcR3 in sera of sepsis patients and its potential role as a clinically important biomarker of sepsis()
por: Kim, Sunghee, et al.
Publicado: (2012)

The siRNA silencing of DcR3 expression induces Fas ligand-mediated apoptosis in HepG2 cells
por: Zhao, Tuanjie, et al.
Publicado: (2018)

Identification and preclinical evaluation of the small molecule, NSC745887, for treating glioblastomas via suppressing DcR3-associated signaling pathways
por: Fann, Li-Yun, et al.
Publicado: (2017)

Effect of DcR3-specific siRNA on cell growth suppression and apoptosis induction in glioma cells via affecting ERK and AKT
por: Zhang, Yu, et al.
Publicado: (2016)

Does DcR1 (TNF-related apoptosis-inducing-ligand Receptor 3) have any role in human AMD pathogenesis?
por: Anand, Akshay, et al.
Publicado: (2014)

Anti‐oral cancer effects of triptolide by downregulation of DcR3 in vitro, in vivo, and in preclinical patient‐derived tumor xenograft model
por: Yang, Cheng‐Yu, et al.
Publicado: (2018)

The β-catenin/TCF-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasis
por: Huang, Wei-Juan, et al.
Publicado: (2020)

DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway
por: Ge, Hua, et al.
Publicado: (2018)

Upregulated TRAIL and Reduced DcR2 Mediate Apoptosis of Decidual PMN-MDSC in Unexplained Recurrent Pregnancy Loss
por: Li, Congcong, et al.
Publicado: (2020)

Spleen Tyrosine Kinase (SYK) in the Progression of Peritoneal Fibrosis Through Activation of the TGF-β1/Smad3 Signaling Pathway
por: Liu, Kang-Han, et al.
Publicado: (2019)

Electrostatic Steering Accelerates C3d:CR2 Association
por: Mohan, Rohith R., et al.
Publicado: (2016)

AMPK inhibits Smad3‐mediated autoinduction of TGF‐β1 in gastric cancer cells
por: Zou, Junrong, et al.
Publicado: (2021)

TRAIL and DcR1 Expressions Are Differentially Regulated in the Pancreatic Islets of STZ- versus CY-Applied NOD Mice
por: Dirice, Ercument, et al.
Publicado: (2011)

Hypermethylation of DcR1 Gene-based Biomarker in Non-invasive Cancer Screening of Vietnamese Cervical Cancer Patients
por: TRUONG, Phuong Kim, et al.
Publicado: (2018)

A new approach to endoscopic DCR
por: Singh, Amit Pal, et al.
Publicado: (2015)

Sildenafil Inhibits the Growth and Epithelial-to-mesenchymal Transition of Cervical Cancer via the TGF-β1/Smad2/3 Pathway
por: Liu, Ping, et al.
Publicado: (2023)

Huangkui Capsule in Combination with Leflunomide Improves Immunoglobulin A Nephropathy by Inhibiting the TGF-β1/Smad3 Signaling Pathway
por: Pei, Shuwen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_nr54am0ftag0oe8csveel5nsh5