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Sirtuin 3-mediated pyruvate dehydrogenase activity determines brown adipocytes phenotype under high-salt conditions

Previous study indicated that Sirtuin 3 (SIRT3) is a central regulator of adaptive thermogenesis in brown adipose tissue (BAT). Here we investigate the role of SIRT3 in the modulation of cellular phenotype in BAT under high salt intake (HS). HS downregulated SIRT3 level in BAT, accompanied by decrea...

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Detalles Bibliográficos
Autores principales:	Wei, Tong, Huang, Gaojian, Liu, Penghao, Gao, Jing, Huang, Chenglin, Sun, Mengwei, Shen, Weili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692335/ https://www.ncbi.nlm.nih.gov/pubmed/31409767 http://dx.doi.org/10.1038/s41419-019-1834-4

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