A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

In this work we model the glomerular filtration barrier, the structure responsible for filtering the blood and preventing the loss of proteins, using human podocytes and glomerular endothelial cells seeded into microfluidic chips. In long-term cultures, cells maintain their morphology, form capillar...

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Detalles Bibliográficos
Autores principales: Petrosyan, Astgik, Cravedi, Paolo, Villani, Valentina, Angeletti, Andrea, Manrique, Joaquin, Renieri, Alessandra, De Filippo, Roger E., Perin, Laura, Da Sacco, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692336/
https://www.ncbi.nlm.nih.gov/pubmed/31409793
http://dx.doi.org/10.1038/s41467-019-11577-z

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