RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection

RIG-I-Like Receptors (RLRs) RIG-I, MDA5, and LGP2, are vital pathogen recognition receptors in the defense against RNA viruses. West Nile Virus (WNV) infections continue to grow in the US. Here, we use a systems biology approach to define the contributions of each RLR in the innate immune response t...

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Detalles Bibliográficos
Autores principales: Stone, Amy E. L., Green, Richard, Wilkins, Courtney, Hemann, Emily A., Gale, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692387/
https://www.ncbi.nlm.nih.gov/pubmed/31409781
http://dx.doi.org/10.1038/s41467-019-11250-5

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