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RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection
RIG-I-Like Receptors (RLRs) RIG-I, MDA5, and LGP2, are vital pathogen recognition receptors in the defense against RNA viruses. West Nile Virus (WNV) infections continue to grow in the US. Here, we use a systems biology approach to define the contributions of each RLR in the innate immune response t...
Autores principales: | Stone, Amy E. L., Green, Richard, Wilkins, Courtney, Hemann, Emily A., Gale, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692387/ https://www.ncbi.nlm.nih.gov/pubmed/31409781 http://dx.doi.org/10.1038/s41467-019-11250-5 |
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