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Rev-Erbα and Photoreceptor Outer Segments modulate the Circadian Clock in Retinal Pigment Epithelial Cells

Retinal photoreceptor outer segments (POS) are renewed daily through phagocytosis by the adjacent retinal pigment epithelial (RPE) monolayer. Phagocytosis is mainly driven by the RPE circadian clock but the underlying molecular mechanisms remain elusive. Using ARPE-19 (human RPE cell-line) dispersed...

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Detalles Bibliográficos
Autores principales:	Milićević, Nemanja, Mazzaro, Nadia, de Bruin, Ivanka, Wils, Esmée, ten Brink, Jacoline, Asbroek, Anneloor ten, Mendoza, Jorge, Bergen, Arthur, Felder-Schmittbuhl, Marie-Paule
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692399/ https://www.ncbi.nlm.nih.gov/pubmed/31409842 http://dx.doi.org/10.1038/s41598-019-48203-3

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