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Structure-based identification of a potential non-catalytic binding site for rational drug design in the fructose 1,6-biphosphate aldolase from Giardia lamblia
Giardia lamblia is the causal agent of giardiasis, one of the most prevalent parasitosis in the world. Even though effective pharmacotherapies against this parasite are available, the disadvantages associated with its use call for the development of new antigiardial compounds. Based on the Giardia d...
Autores principales: | Méndez, Sara-Teresa, Castillo-Villanueva, Adriana, Martínez-Mayorga, Karina, Reyes-Vivas, Horacio, Oria-Hernández, Jesús |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692403/ https://www.ncbi.nlm.nih.gov/pubmed/31409864 http://dx.doi.org/10.1038/s41598-019-48192-3 |
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