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IL-36β Promotes CD8(+) T Cell Activation and Antitumor Immune Responses by Activating mTORC1
Cytokine-amplified functional CD8(+) T cells ensure effective eradication of tumors. Interleukin 36α (IL-36α), IL-36β, and IL-36γ share the same receptor complex, composed of the IL-36 receptor (IL-36R), and IL-1RAcP. Recently, we revealed that IL-36γ greatly promoted CD8(+) T cell activation, contr...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692458/ https://www.ncbi.nlm.nih.gov/pubmed/31447838 http://dx.doi.org/10.3389/fimmu.2019.01803 |