Cargando…

C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis

Psoriasis is one of the most common chronic inflammatory skin diseases, affecting ~2% of the population. The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a recept...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Quan-you, Liang, Shen-ju, Xu, Feng, Li, Gui-qing, Luo, Na, Wu, Shun, Li, You, Tang, Ming, Zhong, Yu, Chen, Jian, Yang, Di, Sun, Dao-dong, Zhang, Ke-qin, Xu, Gui-lian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692472/ https://www.ncbi.nlm.nih.gov/pubmed/31447855 http://dx.doi.org/10.3389/fimmu.2019.01866

Ejemplares similares

The Complement Receptors C3aR and C5aR Are a New Class of Immune Checkpoint Receptor in Cancer Immunotherapy
por: Wang, Yu, et al.
Publicado: (2019)

C5aR deficiency attenuates the breast cancer development via the p38/p21 axis
por: Chen, Jian, et al.
Publicado: (2020)

Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome
por: McCullough, Rebecca L., et al.
Publicado: (2018)

Differential expression of C5aR1 and C5aR2 in innate and adaptive immune cells located in early skin lesions of bullous pemphigoid patients
por: Emtenani, Shirin, et al.
Publicado: (2022)

C5a-C5aR1 Axis Activation Drives Envenomation Immunopathology by the Snake Naja annulifera
por: Silva de França, Felipe, et al.
Publicado: (2021)

Complement C3a Enhances the Phagocytic Activity of B Cells Through C3aR in a Fish
por: Ma, Zi-You, et al.
Publicado: (2022)

Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19
por: Apostolidis, Sokratis A., et al.
Publicado: (2022)

The C5a/C5aR1 Axis Contributes to the Pathogenesis of Acute Cystitis Through Enhancement of Adhesion and Colonization of Uropathogenic E. coli
por: Wu, Kun-Yi, et al.
Publicado: (2022)

Epithelial C5aR1 Signaling Enhances Uropathogenic Escherichia coli Adhesion to Human Renal Tubular Epithelial Cells
por: Song, Yun, et al.
Publicado: (2018)

Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2
por: Karsten, Christian M., et al.
Publicado: (2018)

Advances in pathogenesis and nanoparticles (NPs)-mediated treatment of psoriasis
por: Shen, Qian, et al.
Publicado: (2022)

The Controversial C5a Receptor C5aR2: Its Role in Health and Disease
por: Zhang, Ting, et al.
Publicado: (2017)

Corrigendum to “The Controversial C5a Receptor C5aR2: Its Role in Health and Disease”
por: Zhang, Ting, et al.
Publicado: (2017)

Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections
por: Muenstermann, Marcel, et al.
Publicado: (2019)

C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection
por: Briukhovetska, Daria, et al.
Publicado: (2020)

Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis
por: Su, Wenxing, et al.
Publicado: (2021)

Tumor necrosis factor superfamily 14 is critical for the development of renal fibrosis
por: Li, You, et al.
Publicado: (2020)

The complement receptor C5aR2 regulates neutrophil activation and function contributing to neutrophil-driven epidermolysis bullosa acquisita
por: Seiler, Daniel L., et al.
Publicado: (2023)

The Role of Nociceptive Neurons in the Pathogenesis of Psoriasis
por: Zhang, Xuan, et al.
Publicado: (2020)

Dendritic Cells and Macrophages in the Pathogenesis of Psoriasis
por: Kamata, Masahiro, et al.
Publicado: (2022)

Potential Role of Cytochrome c and Tryptase in Psoriasis and Psoriatic Arthritis Pathogenesis: Focus on Resistance to Apoptosis and Oxidative Stress
por: Chimenti, Maria Sole, et al.
Publicado: (2018)

Interaction of Wnt5a with Notch1 is Critical for the Pathogenesis of Psoriasis
por: Kim, Jeong Eun, et al.
Publicado: (2016)

The “C3aR Antagonist” SB290157 is a Partial C5aR2 Agonist
por: Li, Xaria X., et al.
Publicado: (2021)

C5 deficiency and C5a or C5aR blockade protects against cerebral malaria
por: Patel, Samir N., et al.
Publicado: (2008)

New insights for C5a and C5a receptors in sepsis
por: Yan, Chunguang, et al.
Publicado: (2012)

C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid
por: Hornum, Lars, et al.
Publicado: (2017)

Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors
por: Colley, Caroline S., et al.
Publicado: (2017)

C3a Enhances the Formation of Intestinal Organoids through C3aR1
por: Matsumoto, Naoya, et al.
Publicado: (2017)

Attenuation of cGVHD by C5a/C5aR blockade is associated with increased frequency of Treg
por: Wang, Yulian, et al.
Publicado: (2017)

Role of C5a and C5aR in doxorubicin-induced cardiomyocyte senescence
por: Wen, Yahui, et al.
Publicado: (2021)

The Interplay Between Keratinocytes and Immune Cells in the Pathogenesis of Psoriasis
por: Albanesi, Cristina, et al.
Publicado: (2018)

T Cell Hierarchy in the Pathogenesis of Psoriasis and Associated Cardiovascular Comorbidities
por: Casciano, Fabio, et al.
Publicado: (2018)

Assessing microbial manipulation and environmental pollutants in the pathogenesis of psoriasis
por: Gough, Portia, et al.
Publicado: (2022)

The complement C3a-C3aR and C5a-C5aR pathways promote viability and inflammation of human retinal pigment epithelium cells by targeting NF-κB signaling
por: Luo, Shasha, et al.
Publicado: (2022)

C5aR1 promotes acute pyelonephritis induced by uropathogenic E. coli
por: Li, Ke, et al.
Publicado: (2017)

Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host
por: Verma, Sudha, et al.
Publicado: (2018)

Pan-Cancer Analysis of Immune Complement Signature C3/C5/C3AR1/C5AR1 in Association with Tumor Immune Evasion and Therapy Resistance
por: Lawal, Bashir, et al.
Publicado: (2021)

Comprehensive Analysis of m5C Methylation Regulatory Genes and Tumor Microenvironment in Prostate Cancer
por: Yu, Guopeng, et al.
Publicado: (2022)

Genome-wide DNA methylation of Munro’s microabscess reveals the epigenetic regulation in the pathogenesis of psoriasis
por: Xu, Xiaoqing, et al.
Publicado: (2022)

LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway
por: Zhong, Yu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_q7okar48p1t4rctddrnt1taqan