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Could Dampening Expression of the Neisseria gonorrhoeae mtrCDE-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?

Neisseria gonorrhoeae has developed resistance to every antibiotic introduced for treatment of gonorrhea since 1938, and concern now exists that gonorrheal infections may become refractory to all available antibiotics approved for therapy. The current recommended dual antibiotic treatment regimen of...

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Detalles Bibliográficos
Autores principales: Chen, Shaochun, Connolly, Kristie L., Rouquette-Loughlin, Corinne, D’Andrea, Alexander, Jerse, Ann E., Shafer, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692510/
https://www.ncbi.nlm.nih.gov/pubmed/31409679
http://dx.doi.org/10.1128/mBio.01576-19

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