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How to assess the effectiveness of nasal influenza vaccines? Role and measurement of sIgA in mucosal secretions
Secretory IgAs (sIgA) constitute the principal isotype of antibodies present in nasal and mucosal secretions. They are secreted by plasma cells adjacent to the mucosal epithelial cells, the site where infection occurs, and are the main humoral mediator of mucosal immunity. Mucosally delivered vaccin...
Autores principales: | Gianchecchi, Elena, Manenti, Alessandro, Kistner, Otfried, Trombetta, Claudia, Manini, Ilaria, Montomoli, Emanuele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692539/ https://www.ncbi.nlm.nih.gov/pubmed/31225704 http://dx.doi.org/10.1111/irv.12664 |
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